Ipulse side effects1/9/2024 Very common (10% or more): Local bleeding (15%)Ĭommon (1% to 10%): Injection site hematoma, injection site burning, sensation of tension in the penis, injection site pain Uncommon (0.1% to 1%): Vascular fragility, supraventricular extrasystoles, vein disorder, vasodilatation, peripheral vascular disorder, peripheral edema, swelling of the leg veinsįrequency not reported: Congestive heart failure, hyperemia, second degree heart block, shock, spasm of the right ventricle infundibulum, supraventricular tachycardia, ventricular fibrillation, rapid pulse, pneumopericardium, ventricular hypertrophy, tachyphylaxis, ductus arteriosus histological changes, venous leak, cardiac arrhythmias, postural hypotension, changes in blood pressure, vagal shock, vasovagal reactions, myocardial ischemia Local Very common (10% or more): Flushing (10.1%)Ĭommon (1% to 10%): Bradycardia, hypotension, tachycardia, cardiac arrest, edema, hematoma, hypertension, myocardial infarction, abnormal ECG Rare (less than 0.1%): Urinary tract infectionįrequency not reported: Anuria, abnormal ejaculation, penile deviations, penile warmth, urinary frequency/urinary urgency/impaired urination Cardiovascular Uncommon (0.1% to 1%): Priapism, scrotal erythema, dysuria, hematuria, pollakiuria, micturition urgency, urethral hemorrhage, balanitis, phimosis, ejaculation disorder, scrotal disorder, scrotal pain, testicular swelling, testicular edema, scrotal edema, spermatocele, testicular disorder, testicular mass, penile hemosiderin deposits, swelling of the preputium or the glans, perineal pain, painful erection Very common (10% or more): Penile pain (up to 36%), urethral pain (13%), urethral burning (12%)Ĭommon (1% to 10%): Prolonged erection greater than 4 hours, penile angulation, penile fibrosis, cavernous body fibrosis, Peyronie's disease, penis disorder, prostate disorder, testicular pain, urethral bleeding/spotting and other minor urethral abrasions, vaginal burning/itching The most common side effects were penile pain, local bleeding, fever, urethral pain, urethral burning, apnea, and flushing. Bruising or clotted blood in the penis at the injection site, usually caused by an incorrect injectionĪpplies to alprostadil: compounding powder, injectable kit, injectable powder for injection, injectable solution, transurethral suppository.Bleeding and pain at the injection site (short-term).Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.Ĭheck with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common These side effects may go away during treatment as your body adjusts to the medicine. Some side effects of alprostadil may occur that usually do not need medical attention. erection continuing longer than 6 hours with severe and continuing pain of the penis.Curving of penis with pain during erection.Although not all of these side effects may occur, if they do occur they may need medical attention.Ĭheck with your doctor immediately if any of the following side effects occur while taking alprostadil: Rare Serious side effects of Caverject ImpulseĪlong with its needed effects, alprostadil (the active ingredient contained in Caverject Impulse) may cause some unwanted effects. Some dosage forms listed on this page may not apply to the brand name Caverject Impulse.Īpplies to alprostadil: intracavernosal powder for solution. Note: This document contains side effect information about alprostadil.
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